BiographyManuel Rodriguez-Concepcion is a CSIC Full Professor at IBMCP. He completed his doctoral thesis in 1995 under the supervision of Jose Pio Beltran at the IATA-CSIC in Valencia (Spain). He joined Wilhelm Gruissem’s lab (Univ. California at Berkeley, USA) in 1996. In 1999 he returned to Spain and joined Albert Boronat’s lab (Univ. Barcelona). In 2001, he got a "Ramón y Cajal" award to start an independent group. In 2006 he joined the Centre for Research in Agricultural Genomics (CRAG) in Barcelona (Spain) as a CSIC Associate Professor. He has been a Visiting Professor in sabbatical stays in the laboratories of Jay Keasling (Joint BioEnergy Institute, Berkeley, USA) in 2011 and Ian Paulsen (Macquarie Univ., Sydney, Australia) in 2019. He joined IBMCP in 2020. His research focuses on the metabolic pathways responsible for the synthesis of carotenoids and other isoprenoids in chloroplasts and also in bacteria, their evolutionary ancestors.
1. Ortiz-Alcaide M, Llamas E, Gomez-Cadenas A, Nagatani A, Martinez-Garcia JF, Rodriguez-Concepción M (2019) Chloroplasts modulate elongation responses to shade by retrograde pathways involving HY5 and ABA. PLANT CELL 31: 384-398.
2. Rodriguez-Concepcion M, Avalos J, Bonet ML, Boronat A, Gomez-Gomez L, Hornero-Mendez D, Limon MC, Meléndez-Martínez AJ, Olmedilla-Alonso B, Palou A, Ribot J, Rodrigo MJ, Zacarias L, Zhu C (2018) A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health. PROG. LIPID RES. 70: 62-93.
3. Llamas E, Pulido P, Rodríguez-Concepción M. (2017) Interference with plastome gene expression and Clp protease activity in Arabidopsis triggers a chloroplast unfolded protein response to restore protein homeostasis. PLOS GENET. 13: e1007022.
4. Pulido P, Llamas E, Llorente B, Ventura S, Wright LP, Rodríguez-Concepción M (2016) Specific Hsp100 Chaperones Determine the Fate of the First Enzyme of the Plastidial Isoprenoid Pathway for Either Refolding or Degradation by the Stromal Clp Protease in Arabidopsis. PLOS GENET. 6: 19036.
5. Ruiz-Sola MA, Barja MV, Manzano D, Llorente B, Schipper B, Beekwilder J, Rodríguez-Concepción M (2016) A single Arabidopsis gene encodes two differentially targeted geranylgeranyl diphosphate synthase isoforms. PLANT PHYSIOL. 172: 1393–1402.
6. Llorente B, D’Andrea L, Ruíz-Sola MA, Botterweg E, Pulido P, Andilla J, Loza-Alvarez P, Rodríguez-Concepción M (2016) Tomato fruit carotenoid biosynthesis is adjusted to actual ripening progression by a light-dependent mechanism. PLANT J. 85: 107-119.
7. Bou-Torrent J, Toledo-Ortiz G, Ortiz-Alcaide M, Cifuentes-Esquivel N, Halliday KJ, Martinez-García JF, Rodríguez-Concepción M (2015) Regulation of carotenoid biosynthesis by shade relies on specific subsets of antagonistic transcription factors and co-factors. PLANT PHYSIOL. 169: 1584-1594.
8. Pulido P, Toledo-Ortiz G, Phillips MA, Wright LP, Rodríguez-Concepción M (2013) Arabidopsis J-Protein J20 Delivers the First Enzyme of the Plastidial Isoprenoid Pathway to Protein Quality Control. PLANT CELL 25:4183–4194.
9. Sangari FJ, Pérez-Gil J, Carretero-Paulet L, García-Lobo JM, Rodríguez-Concepción M (2010) A new family of enzymes catalyzing the first committed step of the methylerythritol 4-phosphate (MEP) pathway for isoprenoid biosynthesis in bacteria. PROC. NATL. ACAD. SCI. USA 107: 14081-14086 COVER.
10. Toledo-Ortiz G, Huq E, Rodríguez-Concepción M (2010) Direct regulation of phytoene synthase gene expression and carotenoid biosynthesis by phytochrome-interacting factors. PROC. NATL. ACAD. SCI. USA 107: 11626-11631 COVER.